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Product Details
H00001723-M01
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG2a, lambda
Class
Monoclonal
Type
Antibody
Clone
6E1
Immunogen
DHODH (NP_001352, 32 a.a. approximately 140 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Conjugate
Form
Liquid
Concentration
See Label
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Sequence of this protein is as follows: GDERFYAEHL MPTLQGLLDP ESAHRLAVRF TSLGLLPRAR FQDSDMLEVR VLGHKFRNPV GIAAGFDKHG EAVDGLYKMG FGFVEIGSVT PKPQEGNPRP RVFRLPEDQ
Target Information
The protein encoded by this gene catalyzes the fourth enzymatic step, the ubiquinone-mediated oxidation of dihydroorotate to orotate, in de novo pyrimidine biosynthesis. This protein is a mitochondrial protein located on the outer surface of the inner mitochondrial membrane. [provided by RefSeq, Jul 2008].
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: DHOdehase; Dihydroorotate dehydrogenase (quinone), mitochondrial; Dihydroorotate oxidase; human complement of yeast URA1
Gene Aliases: DHOdehase; DHODH; POADS; URA1
UniProt ID: (Human) Q02127
Entrez Gene ID: (Human) 1723
'de novo' pyrimidine nucleobase biosynthetic process
female pregnancy
lactation
response to caffeine
response to drug
response to starvation
positive regulation of apoptotic process
'de novo' UMP biosynthetic process
pyrimidine nucleoside biosynthetic process
oxidation-reduction process
regulation of mitochondrial fission
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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