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DIAPH1 Antibody (MA5-53192) in ICC/IF
Immunocytochemistry analysis of DIAPH1 in HepG2 cells. Nuclei were stained blue with DAPI; DIAPH1 recombinant monoclonal antibody (Product # MA5-53192) with a dilution of 1:1,000 was stained magenta with Alexa Fluor 647. Images were taken using Leica stellaris 5. Protein abundance based on laser Intensity and smart gain: Medium. Scale bar: 20 μm.
产品信息
MA5-53192
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
Expression System
HEK293F
分类
Recombinant Monoclonal
类型
Antibody
克隆号
23GB1990
抗原
A synthesized peptide derived from human DIAPH1 (1-45AA).
偶联物
形式
Liquid
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
靶标信息
This gene is a homolog of the Drosophila diaphanous gene, and has been linked to autosomal dominant, fully penetrant, nonsyndromic sensorineural progressive low-frequency hearing loss. Actin polymerization involves proteins known to interact with diaphanous protein in Drosophila and mouse. It has therefore been speculated that this gene may have a role in the regulation of actin polymerization in hair cells of the inner ear. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: diaphanous 1; diaphanous homolog 1; diaphanous-1; diaphanous-related formin 1; Diaphanous-related formin-1; DRF1; FLJ25265; mDIA1; p140DIA; p140mDIA; Protein diaphanous homolog 1
基因别名: D18Wsu154e; DFNA1; DIA1; DIAP1; DIAPH1; DRF1; hDIA1; LFHL1; p140mDia; SCBMS
UniProt ID: (Human) O60610, (Mouse) O08808
Entrez Gene ID: (Human) 1729, (Mouse) 13367, (Rat) 307483
cytoskeleton organization
sensory perception of sound
regulation of cell shape
actin filament polymerization
positive regulation of cell migration
regulation of microtubule-based process
protein localization to microtubule
regulation of release of sequestered calcium ion into cytosol
cellular response to histamine
regulation of cell motility
actin cytoskeleton organization
neuron projection development
