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DIO2 Antibody (PA5-100474) in IHC (P)
Immunohistochemistry analysis of DIO2 in human ovarian cancer. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. Samples were incubated with DIO2 polyclonal antibody (Product # PA5-100474) using a dilution of 1:100 (4°C overnight) followed by HRP conjugated anti-Rabbit secondary antibody.
产品信息
PA5-100474
产品规格
种属反应
Human,
Mouse,
Rat
已发表种属
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human DIO2(Accession Q92813), corresponding to amino acid residues H36-S57.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice
RRID
AB_2849984
产品详细信息
Antibody detects endogenous levels of total DIO2.
靶标信息
The protein encoded by this gene belongs to the iodothyronine deiodinase family. It activates thyroid hormone by converting the prohormone thyroxine by outer ring deiodination to bioactive 3,3',5-triiodothyronine residues encoded by the UGA codon, which normally signals translation termination. The 3' UTR of Sec-containing genes have a common stem-loop structure, the sec insertion sequence, which is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. Alternative splicing results in multiple transcript variants encoding different isoforms.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: 5DII; deiodinase, iodothyronine, type 2; deiodinase-2; deiodonase-2; DIOII; iodothyronine type II deiodinase; thyroxine deiodinase; thyroxine deiodinase, type II; thyroxine type II; Type 2 DI; type 2 iodothyronine deiodinase; Type II iodothyronine deiodinase; type-II 5' deiodinase; Type-II 5'-deiodinase; type-II 5'deiodinase
基因别名: 5DII; AI324267; D2; DIO2; DIOII; ITDI2; SelY; TXDI2
UniProt ID: (Human) Q92813, (Mouse) Q9Z1Y9, (Rat) P70551
Entrez Gene ID: (Human) 1734, (Mouse) 13371, (Rat) 65162
