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产品信息
PA5-41948
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide directed towards the N-terminal of human MGC42174 (aa 121-170).
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein A
保存液
PBS with 2% sucrose
内含物
0.09% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2606799
产品详细信息
Peptide sequence: WKVVKPESND KETEAAYESD IPEELCGHHL PQQSLKSYND SPDVIVEAQF
Sequence homology: Cow: 93%; Dog: 86%; Guinea Pig: 86%; Horse: 86%; Human: 100%; Mouse: 86%; Pig: 93%; Rabbit: 79%; Rat: 86%
靶标信息
DIS3L2 encodes a protein that is similar in sequence to 3'/5' exonucleolytic subunits of the RNA exosome. The exosome is a large multimeric ribonucleotide complex responsible for degrading various RNA substrates. Several transcript variants, some protein-coding and some not, have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: DIS3 mitotic control homolog-like 2; DIS3-like exonuclease 2; DIS3L2; family with sequence similarity 6, member A; hDIS3L2
基因别名: DIS3L2; FAM6A; hDIS3L2; PRLMNS
UniProt ID: (Human) Q8IYB7
Entrez Gene ID: (Human) 129563
nuclear-transcribed mRNA catabolic process, exonucleolytic
rRNA processing
mitotic nuclear division
negative regulation of cell proliferation
miRNA catabolic process
rRNA catabolic process
stem cell population maintenance
nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5'
cell division
mitotic sister chromatid separation
RNA phosphodiester bond hydrolysis, exonucleolytic
polyuridylation-dependent mRNA catabolic process
