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Product Details
PA5-72744
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
DISP1 antibody for a 16 amino acid synthetic peptide near the amino terminus of human DISP1. The immunogen is within amino acids 20 - 70 of DISP1.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2718598
Target Information
The pattern of cellular proliferation and differentiation that leads to normal development of embryonic structures often depends upon the localized production of secreted protein signals. Cells surrounding the source of a particular signal respond in a graded manner according to the effective concentration of the signal, and this response produces the pattern of cell types constituting the mature structure. A novel segment-polarity gene known as dispatched has been identified in Drosophila and its protein product is required for normal Hedgehog signaling. This gene is one of two human homologs of Drosophila dispatched and, based on sequence identity to its mouse counterpart, the encoded protein may play an essential role in Hh patterning activities in the early embryo.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: dispatched A; dispatched homolog 1; DKFZP434I0428; FLJ43740; Mdispa; MGC104180; MGC13130; MGC16796; Protein dispatched homolog 1; twelve-pass transmembrane protein
Gene Aliases: 1190008H24Rik; Disp; DISP1; DISPA; Icb; Icbins
UniProt ID: (Human) Q9H698, (Mouse) Q3TDN0
Entrez Gene ID: (Human) 84976, (Mouse) 68897
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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