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产品信息
PA5-72638
应用
建议稀释比
已发表文章
产品规格
种属反应
Zebrafish
已发表种属
Zebrafish
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
KLH conjugated synthetic peptide between 120-149 amino acids from the C-terminal region of DANRE park7
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Protein A, Antigen affinity chromatography
保存液
PBS, pH 7.4
内含物
0.09% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2718492
靶标信息
The product of this gene belongs to the peptidase C56 family of proteins. It acts as a positive regulator of androgen receptor-dependent transcription. It may also function as a redox-sensitive chaperone, as a sensor for oxidative stress, and it apparently protects neurons against oxidative stress and cell death. Defects in this gene are the cause of autosomal recessive early-onset Parkinson disease 7. Two transcript variants encoding the same protein have been identified for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: CTA-215D11.1; DJ-1 protein; early onset 7; FLJ27376; FLJ34360; FLJ92274; Maillard deglycase; OTTHUMP00000001350; OTTHUMP00000001351; PARK7 GENE; PARK7/DJ1; parkinson disease (autosomal recessive, early onset) 7; Parkinson disease protein 7 homolog; Parkinsonism-associated deglycase; protein deglycase DJ-1zDJ-1; protein DJ-1; Protein DJ-1zDJ-1; Protein/nucleic acid deglycase DJ-1; zDJ-1
基因别名: dj1; park7; zgc:103725
UniProt ID: (Zebrafish) Q5XJ36
Entrez Gene ID: (Zebrafish) 449674
DNA repair
proteolysis
protein deglycosylation
autophagy
inflammatory response
response to oxidative stress
single fertilization
methylglyoxal metabolic process
insulin secretion
cellular response to oxidative stress
protein deglycation, glyoxal removal
protein deglycation, methylglyoxal removal
glucose homeostasis
regulation of neuron apoptotic process
protein stabilization
negative regulation of cell death
cellular response to hydrogen peroxide
guanine deglycation, methylglyoxal removal
guanine deglycation, glyoxal removal
negative regulation of reactive oxygen species biosynthetic process
positive regulation of oxidative phosphorylation uncoupler activity
