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DLL1 Antibody (PA5-85819) in WB
Western blot analysis of DLL1 in mouse tissue extract using DLL1 polyclonal antibody (Product # PA5-85819) using 50 µg of sample at a dilution of 1:100. Sample was then incubated with HRP-conjugated anti-rabbit IgG secondary antibody. Prior to incubation with primary antibody, the sample was separated on 7.5% SDS-PAGE.
产品信息
PA5-85819
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant protein encompassing a sequence within the center region of Human DLL1.
偶联物
形式
Liquid
浓度
0.81 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7, with 20% glycerol
内含物
0.025% ProClin 300
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2792955
产品详细信息
Keep as concentrated solution.
Predicted reactivity: Mouse (87%), Rat (84%), Chicken (81%).
Positive Control: mouse heart.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
靶标信息
Delta-like protein 1 (DLL1) is a transmembrane protein characterized by epidermal growth factor (EGF)-like repeats. It is a ligand for Notch receptor. It blocks the differentiation of progenitor cells into the B-cell lineage while promoting the emergence of a population of cells with the characteristics of a T-cell/NK-cell precursor.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: delta like-1; Delta-like protein 1; Delta1; Drosophila Delta homolog 1; H-Delta-1; OTTHUMP00000017690
基因别名: Delta; DELTA1; DL1; DLL1; UNQ146/PRO172
UniProt ID: (Human) O00548, (Mouse) Q61483
Entrez Gene ID: (Human) 28514, (Mouse) 13388
in utero embryonic development
somitogenesis
somite specification
heart looping
cell communication
Notch signaling pathway
cell-cell signaling
multicellular organism development
determination of left/right symmetry
compartment pattern specification
nervous system development
organ morphogenesis
auditory receptor cell fate commitment
cell differentiation
negative regulation of interleukin-10 production
inner ear morphogenesis
odontogenesis of dentin-containing tooth
auditory receptor cell differentiation
negative regulation of cell differentiation
negative regulation of auditory receptor cell differentiation
negative regulation of myeloid cell differentiation
negative regulation of neuron differentiation
positive regulation of Notch signaling pathway
positive regulation of transcription from RNA polymerase II promoter
inner ear development
regulation of neurogenesis
Notch signaling involved in heart development
left/right axis specification
cell fate determination
marginal zone B cell differentiation
type B pancreatic cell development
Notch receptor processing
regulation of blood pressure
positive regulation of cell proliferation
negative regulation of cell proliferation
proximal/distal pattern formation
astrocyte development
regulation of somitogenesis
spinal cord development
cerebellar molecular layer formation
cerebellar Purkinje cell layer structural organization
hemopoiesis
regulation of cell adhesion
negative regulation of epithelial cell differentiation
negative regulation of glial cell apoptotic process
organ growth
regulation of growth
negative regulation of epidermal cell differentiation
negative regulation of myoblast differentiation
positive regulation of endocytosis
lateral inhibition
skeletal muscle tissue growth
regulation of skeletal muscle tissue growth
positive regulation of skeletal muscle tissue growth
neuron fate specification
regulation of cell division
retina development in camera-type eye
retina morphogenesis in camera-type eye
Notch signaling pathway involved in arterial endothelial cell fate commitment
nephron development
proximal tubule development
loop of Henle development
clathrin-mediated endocytosis
endothelial tip cell fate specification
neuronal stem cell population maintenance
skin epidermis development
regulation of vascular endothelial growth factor signaling pathway
positive regulation of sprouting angiogenesis
regulation of energy homeostasis
