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产品信息
PA5-40612
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide directed towards the C-terminal of human DLX1 (aa 182-231).
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS with 2% sucrose
内含物
0.09% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2608471
产品详细信息
Peptide sequence: KFKKLMKQGG AALEGSALAN GRALSAGSPP VPPGWNPNSS SGKGSGGNAG
Sequence homology: Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 93%; Rat: 100%
靶标信息
This gene encodes a member of a homeobox transcription factor gene family similiar to the Drosophila distal-less gene. The encoded protein is localized to the nucleus where it may function as a transcriptional regulator of signals from multiple TGF-beta superfamily members. The encoded protein may play a role in the control of craniofacial patterning and the differentiation and survival of inhibitory neurons in the forebrain. This gene is located in a tail-to-tail configuration with another member of the family on the long arm of chromosome 2. Alternatively spliced transcript variants encoding different isoforms have been described.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: distal-less homeo box 1; Homeobox protein DLX-1
基因别名: DLX1
UniProt ID: (Human) P56177
Entrez Gene ID: (Human) 1745
negative regulation of transcription from RNA polymerase II promoter
proximal/distal pattern formation
subpallium development
hippocampus development
regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment
cerebral cortex GABAergic interneuron fate commitment
odontogenesis of dentin-containing tooth
negative regulation of neuron apoptotic process
negative regulation of Notch signaling pathway
embryonic skeletal system development
negative regulation of oligodendrocyte differentiation
