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产品信息
H00001746-M07
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG2a, kappa
分类
Monoclonal
类型
Antibody
克隆号
3H3
抗原
DLX2 (NP_004396, 1 a.a. approximately 124 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
偶联物
形式
Liquid
浓度
See Label
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Sequence of this protein is as follows: MTGVFDSLVA DMHSTQIAAS STYHQHQQPP SGGGAGPGGN SSSSSSLHKP QESPTLPVST ATDSSYYTNQ QHPAGGGGGG GSPYAHMGSY QYQASGLNNV PYSAKSSYDL GYTAAYTSYA PYGT
靶标信息
Many vertebrate homeo box-containing genes have been identified on the basis of their sequence similarity with Drosophila developmental genes. Members of the Dlx gene family contain a homeobox that is related to that of Distal-less (Dll), a gene expressed in the head and limbs of the developing fruit fly. The Distal-less (Dlx) family of genes comprises at least 6 different members, DLX1-DLX6. The DLX proteins are postulated to play a role in forebrain and craniofacial development. This gene is located in a tail-to-tail configuration with another member of the gene family on the long arm of chromosome 2.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: distal-less homeo box 2; Homeobox protein DLX-2
基因别名: DLX2; TES-1; TES1
UniProt ID: (Human) Q07687
Entrez Gene ID: (Human) 1746
RNA polymerase II regulatory region sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding
chromatin binding
transcription factor activity, sequence-specific DNA binding
single-stranded RNA binding
protein binding
homeodomain transcription factor
negative regulation of transcription from RNA polymerase II promoter
transcription from RNA polymerase II promoter
brain development
proximal/distal pattern formation
subpallium development
hippocampus development
olfactory bulb development
regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment
cerebral cortex GABAergic interneuron fate commitment
odontogenesis of dentin-containing tooth
negative regulation of Notch signaling pathway
positive regulation of transcription from RNA polymerase II promoter
embryonic cranial skeleton morphogenesis
negative regulation of oligodendrocyte differentiation
branching morphogenesis of a nerve
cartilage development
