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DMC1 Antibody (PA5-21472) in IHC (P)
DMC1 Polyclonal Antibody detects DMC1 protein at nucleolus on mouse testis by immunohistochemical analysis. Sample: Paraffin-embedded mouse testis. DMC1 Polyclonal Antibody (Product # PA5-21472) dilution: 1:500. Antigen Retrieval: EDTA based buffer, pH 8.0, 15 min.
Product Details
PA5-21472
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Published species
Sea urchin
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fragment corresponding to a region within amino acids 1 and 206 of DMC1 (Uniprot ID#Q14565)
Conjugate
Form
Liquid
Concentration
0.9 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
0.1M tris glycine, pH 7, with 20% glycerol
Contains
0.01% thimerosal
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_11152849
Product Specific Information
Recommended positive controls: 293T, HeLa, Molt-4, Raji, mouse testis.
Predicted reactivity: Mouse (94%), Rat (95%), Zebrafish (83%), Japanese Medaka (84%), Bovine (98%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
DMC1 is essential for meiotic homologous recombination. Genetic recombination in meiosis plays an important role in generating diversity of genetic information. The product of this protein is structurally and evolutionary related to the products of the yeast RAD51 and E. coli RecA genes.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: disrupted meiotic cDNA 1 homolog; disrupted meiotic cDNA1, yeast, homolog of; DMC 1; DMC1 dosage suppressor of mck1 homolog, meiosis-specific homologous recombination; DMC1 homologue; HsLim15; Meiotic recombination protein DMC1/LIM15 homolog; MGC150472; MGC150473; RP1-199H16.4
Gene Aliases: dJ199H16.1; DMC1; DMC1H; LIM15; Mei11; sgdp
UniProt ID: (Human) Q14565, (Mouse) Q61880
Entrez Gene ID: (Human) 11144, (Mouse) 13404
DNA recombinase assembly
ovarian follicle development
oocyte maturation
mitotic recombination
meiotic nuclear division
synapsis
reciprocal meiotic recombination
male meiosis I
spermatogenesis
spermatid development
female gamete generation
response to ionizing radiation
strand invasion
chromosome organization involved in meiotic cell cycle
DNA metabolic process
DNA repair
cell cycle
gamete generation
meiotic cell cycle
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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