Invitrogen

DMRT1 Polyclonal Antibody

查看其他11个DMRT1抗体

抗体检测数据 (1)

DMRT1 Antibody in Western Blot (WB)

DMRT1 Antibody in Western Blot (WB)

图: 1 / 1

DMRT1 Antibody (PA5-40351) in WB

Western blot analysis of human esophagus tumor cell lysate using an anti-DMRT1 polyclonal antibody (Product # PA5-40351).

DMRT1 Antibody in Western Blot (WB)

Product Image Gallery

DMRT1 Antibody in Western Blot (WB) — Western blot analysis of human esophagus tumor cell lysate using an anti-DMRT1 polyclonal antibody (Product # PA5-40351).

产品信息

PA5-40351

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1 µg/mL

-

产品规格

种属反应

Human

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

Synthetic peptide directed towards the middle region of human DMRT1

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.5 mg/mL

纯化类型

Affinity Chromatography

保存液

PBS with 2% sucrose

内含物

0.09% sodium azide

保存条件

-20° C, Avoid Freeze/Thaw Cycles

运输条件

Wet ice

AB_2576310

产品详细信息

Peptide sequence: GSPVKNSLRG LPGPYVPGQT GNQWQMKNME NRHAMSSQYR MHSYYPPPSY

Sequence homology: Cow: 93%; Dog: 93%; Guinea Pig: 86%; Horse: 93%; Human: 100%; Mouse: 77%; Rabbit: 92%; Rat: 92%

靶标信息

This gene is found in a cluster with two other members of the gene family, having in common a zinc finger-like DNA-binding motif (DM domain). The DM domain is an ancient, conserved component of the vertebrate sex-determining pathway that is also a key regulator of male development in flies and nematodes. This gene exhibits a gonad-specific and sexually dimorphic expression pattern. Defective testicular development and XY feminization occur when this gene is hemizygous.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

篇参考文献 (0)

您是否在文献中引用过该产品？请点击下方按钮邮件告知我们。

引用该产品

生物信息学

蛋白别名: DM domain expressed in testis 1; DM domain expressed in testis protein 1; Doublesex- and mab-3-related transcription factor 1

查看更多收起

基因别名: CT154; DMRT1; DMT1

查看更多收起

UniProt ID: (Human) Q9Y5R6

查看更多收起

Entrez Gene ID: (Human) 1761

查看更多收起

RNA polymerase II regulatory region sequence-specific DNA binding core promoter proximal region sequence-specific DNA binding transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding chromatin binding transcription factor activity, sequence-specific DNA binding protein homodimerization activity metal ion binding protein heterodimerization activity DNA-binding transcription factor

negative regulation of transcription from RNA polymerase II promoter cell morphogenesis male germ cell proliferation transcription from RNA polymerase II promoter spermatogenesis sex differentiation germ cell migration male sex determination intracellular signal transduction negative regulation of meiotic nuclear division positive regulation of mitotic nuclear division positive regulation of transcription from RNA polymerase II promoter male sex differentiation oocyte development Sertoli cell differentiation Sertoli cell development positive regulation of meiosis I regulation of nodal signaling pathway positive regulation of male gonad development