Invitrogen

DMRT1 Polyclonal Antibody

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DMRT1 Antibody (PA5-97042) in WB

Western blot analysis of DMRT1 in various lysates. Samples were incubated with DMRT1 Polyclonal antibody (Product # PA5-97042) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.

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产品信息

PA5-97042

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:500-1:1,000

酶联免疫吸附实验 (ELISA)

1 µg/mL

产品规格

种属反应

Human

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

Recombinant fusion protein containing a sequence corresponding to amino acids 134-373 of human DMRT1 (NP_0687702)

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.62 mg/mL

纯化类型

Affinity Chromatography

保存液

PBS, pH 7.3, with 50% glycerol

内含物

0.02% sodium azide

保存条件

-20° C, Avoid Freeze/Thaw Cycles

运输条件

Wet ice

AB_2808844

产品详细信息

Immunogen sequence: SHPIPLPSAA ELLVKRENNG SNPCLMTECS GTSQPPPASV PTTAASEGRM VIQDIPAVTS RGHVENTPDL VSDSTYYSSF YQPSLFPYYN NLYNCPQYSM ALAADSASGE VGNPLGGSPV KNSLRGLPGP YVPGQTGNQW QMKNMENRHA MSSQYRMHSY YPPPSYLGQS VPQFFTFEDA PSYPEARASV FSPPSSQDSG LVSLSSSSPI SNKSTKAVLE CEPASEPSSF TVTPVIEEDE; Positive Samples: HL-60; Cellular Location: Nucleus

靶标信息

This gene is found in a cluster with two other members of the gene family, having in common a zinc finger-like DNA-binding motif (DM domain). The DM domain is an ancient, conserved component of the vertebrate sex-determining pathway that is also a key regulator of male development in flies and nematodes. This gene exhibits a gonad-specific and sexually dimorphic expression pattern. Defective testicular development and XY feminization occur when this gene is hemizygous.

仅用于科研。不用于诊断过程。未经明确授权不得转售。