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产品信息
PA5-57971
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
形式
Liquid
浓度
0.3 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2640650
产品详细信息
Immunogen sequence: TVLSTGMDNR YLVLAVNTVQ NKEGNCEKRL VITASQSLEN KELCILRNDW CSVPVEPGDI IHLEGDCTSD TWIIDKDFGY LILY
Highest antigen sequence identity to the following orthologs: Mouse - 74%, Rat - 69%.
靶标信息
DNA2 is a conserved helicase/nuclease involved in themaintenance of mitochondrial and nuclear DNA stability.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: DNA replication ATP-dependent helicase-like homolog; DNA replication ATP-dependent helicase/nuclease DNA2; DNA replication helicase 2 homolog; DNA2-like helicase; hDNA2
基因别名: DNA2; DNA2L; hDNA2; KIAA0083
UniProt ID: (Human) P51530
Entrez Gene ID: (Human) 1763
DNA binding
DNA helicase activity
helicase activity
nuclease activity
protein binding
ATP binding
ATPase activity
site-specific endodeoxyribonuclease activity, specific for altered base
5'-flap endonuclease activity
5'-3' DNA helicase activity
single-stranded DNA-dependent ATPase activity
metal ion binding
4 iron, 4 sulfur cluster binding
DNA replication checkpoint
telomere maintenance via recombination
telomere maintenance
DNA double-strand break processing
DNA synthesis involved in DNA repair
strand displacement
DNA replication
mitochondrial DNA replication
base-excision repair
DNA duplex unwinding
DNA replication, Okazaki fragment processing
DNA replication, removal of RNA primer
mitochondrial DNA repair
positive regulation of DNA replication
nucleic acid phosphodiester bond hydrolysis
regulation of signal transduction by p53 class mediator
mitotic telomere maintenance via semi-conservative replication
