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产品信息
PA5-68743
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
synthetic peptide directed towards the middle region of human DNA2
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Affinity chromatography
保存液
PBS with 2% sucrose
内含物
0.09% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2689359
产品详细信息
This target displays homology in the following species: Cow: 92%; Dog: 93%; Guinea Pig: 85%; Horse: 86%; Human: 100%; Mouse: 93%; Pig: 93%; Rabbit: 85%; Rat: 86%
靶标信息
DNA2 is a conserved helicase/nuclease involved in themaintenance of mitochondrial and nuclear DNA stability.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: DNA replication ATP-dependent helicase-like homolog; DNA replication ATP-dependent helicase/nuclease DNA2; DNA replication helicase 2 homolog; DNA2-like helicase; hDNA2
基因别名: DNA2; DNA2L; hDNA2; KIAA0083
UniProt ID: (Human) P51530
Entrez Gene ID: (Human) 1763
DNA binding
DNA helicase activity
helicase activity
nuclease activity
protein binding
ATP binding
ATPase activity
site-specific endodeoxyribonuclease activity, specific for altered base
5'-flap endonuclease activity
5'-3' DNA helicase activity
single-stranded DNA-dependent ATPase activity
metal ion binding
4 iron, 4 sulfur cluster binding
DNA replication checkpoint
telomere maintenance via recombination
telomere maintenance
DNA double-strand break processing
DNA synthesis involved in DNA repair
strand displacement
DNA replication
mitochondrial DNA replication
base-excision repair
DNA duplex unwinding
DNA replication, Okazaki fragment processing
DNA replication, removal of RNA primer
mitochondrial DNA repair
positive regulation of DNA replication
nucleic acid phosphodiester bond hydrolysis
regulation of signal transduction by p53 class mediator
mitotic telomere maintenance via semi-conservative replication
