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Immunogen sequence: EKEKAKTPVA KKSGKMAMRK LTSMESQTDD LIKLSQAAKI MERMVNQNTY DDIAQDFKYY DDAADEYRDQ VGTLLPLWKF QNDKAKRLSV TALCW
Highest antigen sequence identity to the following orthologs: Mouse - 86%, Rat - 86%.
Eukaryotic cells rely on actin and microtubule-based protein "motors" to generate intracellular movements. These protein "motors" contain specialized domains that hydrolyze ATP to produce force and movement along a cytoskeletal polymer (actin in the case of myosin family and microtubules in the case of the kinesin family and dyneins). Dynein has been implicated in cytoplasmic motile functions, including chromosomal movement, retrograde organelle and axonal transport, the endocytic pathway, and the organization of the Golgi apparatus. In all cell types, dynein has the same basic structures and is composed of two or three distinct heavy chains (~450 kDa), three intermediate chains (70-125 kDa), and at least four light chains (15-25 kDa).
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Axonemal dynein intermediate chain 1; Dynein axonemal intermediate chain 1; dynein, axonemal, intermediate chain 1; dynein, axonemal, intermediate polypeptide 1; ICS; immotile cilia syndrome 1; MGC26204; RP11-296L22.2; testis tissue sperm-binding protein Li 87P
基因别名: CILD1; DIC1; DNAI1; ICS1; PCD
UniProt ID: (Human) Q9UI46
Entrez Gene ID: (Human) 27019