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DNAJB6 Antibody (MA5-27342) in IHC (P)
Immunohistochemistry was performed on paraffin-embedded human embryonic cerebellum tissue. To expose target proteins, heat-induced epitope retrieval by 1mM EDTA in 10mM Tris buffer (pH8.5) at 120°C for 3 min. Following antigen retrieval, tissues were probed with a DNAJB6 monoclonal antibody (Product # MA5-27342) at a dilution of 1:150.
产品信息
MA5-27342
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Mouse
/ IgG2b
分类
Monoclonal
类型
Antibody
克隆号
OTI5B5
抗原
Full length human recombinant protein of DNAJB6 produced in HEK293T
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 1% BSA, 50% glycerol
内含物
0.02% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2723077
靶标信息
This gene encodes a member of the DNAJ protein family. DNAJ family members are characterized by a highly conserved amino acid stretch called the 'J-domain' and function as one of the two major classes of molecular chaperones involved in a wide range of cellular events, such as protein folding and oligomeric protein complex assembly. This family member may also play a role in polyglutamine aggregation in specific neurons. Alternative splicing of this gene results in multiple transcript variants; however, not all variants have been fully described.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: DnaJ (Hsp40) homolog, subfamily B, member 6; DnaJ homolog subfamily B member 6; DnaJ-like 2 protein; dnajb6 {ECO:0000312|EMBL:AAH78908.1, ECO:0000312|RGD:1308207}; Heat shock protein J2; HHDJ1; HSJ-2; Hsp40 homolog; mammalian relative of DnaJ; mDj4; MRJ; MSJ-1
基因别名: DJ4; DnaJ; DNAJB6; HHDJ1; HSJ-2; HSJ2; LGMD1D; LGMD1E; mDj4; MRJ; MSJ-1; MSJ1
UniProt ID: (Human) O75190, (Mouse) O54946, (Rat) Q6AYU3
Entrez Gene ID: (Human) 10049, (Mouse) 23950, (Rat) 362293
protein folding
actin cytoskeleton organization
extracellular matrix organization
positive regulation of ATPase activity
regulation of protein localization
protein localization to nucleus
negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
intermediate filament organization
negative regulation of transcription, DNA-templated
chorio-allantoic fusion
syncytiotrophoblast cell differentiation involved in labyrinthine layer development
chorion development
negative regulation of inclusion body assembly
regulation of cellular response to heat
chaperone-mediated protein folding
