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产品信息
PA1-30778
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Peptide corresponding to aa 347- 360 of human DNase II precursor (accession no. AF047016).
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.4
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2095542
产品详细信息
Recommended positive controls: Human spleen tissue lysate.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
靶标信息
DNase II is a member of the DNase family. The protein, located in the lysosome, hydrolyzes DNA under acidic conditions and mediates the breakdown of DNA during erythropoiesis and apoptosis. Two codominant alleles have been characterized, DNASE2*L (low activity) and DNASE2*H (high activity), that differ at one nucleotide in the promoter region. The DNASE2*H allele is represented in this record.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Acid DNase; deoxyribonuclease; Deoxyribonuclease II alpha; Deoxyribonuclease-2-alpha; DNase II alpha; DNase II, lysosomal; Lysosomal DNase II; R31240_2
基因别名: DNASE2; DNASE2A; DNL; DNL2
UniProt ID: (Human) O00115
Entrez Gene ID: (Human) 1777
