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DOC2B Antibody (PA5-100484) in IHC (P)
Immunohistochemistry analysis of DOC2B in mouse kidney tissue. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. Samples were incubated with DOC2B polyclonal antibody (Product # PA5-100484) using a dilution of 1:100 (4°C overnight) followed by HRP conjugated anti-Rabbit secondary antibody.
产品信息
PA5-100484
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human DOC2B(Accession Q14184), corresponding to amino acid residues Q85-L135.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice
RRID
AB_2849994
产品详细信息
Antibody detects endogenous levels of total DOC2B.
靶标信息
There are at least two protein isoforms of the Double C2 protein, namely alpha and beta, which contain two C2-like domains. DOC2A and DOC2B are encoded by different genes; these genes are at times confused with the unrelated DAB2 gene which was initially named DOC-2. DOC2B is expressed ubiquitously and is suggested to be involved in Ca-dependent intracellular vesicle trafficking in various types of cells.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Doc2-beta; double C2 protein beta; double C2, beta; Double C2-like domain-containing protein beta; double C2-like domains, beta; OTTMUSP00000006522
基因别名: DOC2B; DOC2BL
UniProt ID: (Human) Q14184, (Mouse) P70169, (Rat) P70610
Entrez Gene ID: (Human) 8447, (Mouse) 13447, (Rat) 81820
vesicle fusion
protein localization
regulation of calcium ion-dependent exocytosis
positive regulation of vesicle fusion
positive regulation of insulin secretion
positive regulation of calcium ion-dependent exocytosis
calcium ion-regulated exocytosis of neurotransmitter
synaptic vesicle exocytosis
exocytosis
