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产品信息
PA5-21291
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide corresponding to a region within amino acids 1802 and 1865 of DOCK1
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7, with 20% glycerol
内含物
0.01% thimerosal
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_11153260
产品详细信息
Recommended positive controls: 293T, HeLaS3, PC-12, C8D30, NIH-3T3, Raw264.7, C2C12.
Predicted reactivity: Mouse (100%), Rat (100%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
靶标信息
This gene encodes a loosely associated peripheral membrane protein related to the LanC family of bacterial membrane-associated proteins involved in the biosynthesis of antimicrobial peptides. This protein may play a role as a peptide-modifying enzyme component in eukaryotic cells. Previously considered a member of the G-protein-coupled receptor superfamily, this protein is now in the LanC family. Multiple alternatively spliced variants, encoding the same protein, have been identified.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 180 kDa protein downstream of CRK; dedicator of cyto-kinesis 1; Dedicator of cytokinesis protein 1; dock 180; DOCK180; DOwnstream of CrK; RP11-82L9.1
基因别名: 9130006G06Rik; AI854900; ced5; D630004B07Rik; DOCK1; DOCK180; RGD1566072
UniProt ID: (Human) Q14185, (Mouse) Q8BUR4
Entrez Gene ID: (Human) 1793, (Mouse) 330662, (Rat) 309081
hematopoietic progenitor cell differentiation
phagocytosis
apoptotic process
small GTPase mediated signal transduction
cell migration
phagocytosis, engulfment
cytoskeleton organization
signal transduction
integrin-mediated signaling pathway
blood coagulation
positive regulation of epithelial cell migration
Fc-gamma receptor signaling pathway involved in phagocytosis
positive regulation of GTPase activity
vascular endothelial growth factor receptor signaling pathway
positive regulation of substrate adhesion-dependent cell spreading
