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DOCK2 Antibody (H00001794-M01) in PLA
Proximity Ligation Analysis of protein-protein interactions between CD247 and DOCK2. HeLa cells were stained with anti-CD247 rabbit purified polyclonal 1:1200 and anti-DOCK2 mouse monoclonal antibody 1:50. Each red dot represents the detection of protein-protein interaction complex, and nuclei were counterstained with DAPI (blue).
产品信息
H00001794-M01
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG2a, kappa
分类
Monoclonal
类型
Antibody
克隆号
2F4
抗原
DOCK2 (AAH16996, 1 a.a. approximately 336 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
偶联物
形式
Liquid
浓度
See Label
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Sequence of this protein is as follows: MCVCAEDGKT LPVAVPIEDM QRIHLRFMFR HRSSLESKDK GEKNFAMSYV KLMKEDGTTL HDGFHDLVVL KGDSKKMEDA SAYLTLPSYR HHVENKGATL SRSSSSVGGL SVSSRDVFSI STLVCSTKLT QNVGLLGLLK WRMKPQLEES MRRLFESINN LMKSQYKTTI LLQVAALKYI PSVLHDVEMV FDAKLLSQLL YEFYTCIPPV KLQKQKVQSM NEIVQSNLFK KQECRDILLP VITKELKELL EQKDDMQHQV LERKYCVELL NSILEVLSYQ DAAFTYHHIQ EIMVQLLRTV NRTVITMGRD HILIGACCNC GFPSSTPHSL IQWLWG
靶标信息
The DOCK2 gene encodes a hematopoietic cell-specific CDM family protein that is indispensable for lymphocyte chemotaxis.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: dedicator of cyto-kinesis 2; Dedicator of cytokinesis protein 2; FLJ46592
基因别名: DOCK2; IMD40; KIAA0209
UniProt ID: (Human) Q92608
Entrez Gene ID: (Human) 1794
membrane raft polarization
establishment of T cell polarity
immunological synapse formation
myeloid dendritic cell activation involved in immune response
chemotaxis
small GTPase mediated signal transduction
actin cytoskeleton organization
positive regulation of GTPase activity
macropinocytosis
positive thymic T cell selection
negative thymic T cell selection
alpha-beta T cell proliferation
regulation of defense response to virus by virus
positive regulation of phagocytosis
