Search Thermo Fisher Scientific
图: 1 / 3
Antibody detects endogenous levels of total DOCK8.
The Dedicator of cytokinesis protein 8 (DOCK8) is a member of the DOCK180 family of guanine nucleotide exchange factors. DOCK8 plays an essential role in humoral immune responses and is important in the proper formation of the B cell immunological synapse. Mutations in this gene result in the autosomal recessive form of the hyper-IgE syndrome.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: 1200017A24Rik; Dedicator of cytokinesis protein 8; epididymis luminal protein 205
基因别名: 1200017A24Rik; 5830472H07Rik; A130095G14Rik; AI461977; DOCK8; HEL-205; MRD2; ZIR8
UniProt ID: (Human) Q8TEP1, (Mouse) Q8C147
Entrez Gene ID: (Human) 81704, (Mouse) 76088, (Rat) 499337