Invitrogen

DOK7 Polyclonal Antibody

DOK7 Antibody in Immunocytochemistry (ICC/IF)

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DOK7 Antibody (PA5-84565) in ICC/IF

Immunofluorecent analysis of DOK7 in human cell line MCF7 using DOK7 Polyclonal Antibody (Product # PA5-84565). Staining shows localization to nucleus.

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DOK7 Antibody — Relative expression in western blot: Antibody specificity was demonstrated by detection of known differential basal expression of the target across tissue/cell models. Expression of DOK7 was observed specifically in MCF-7 cells and in SK-MEL-30 cells using anti-DOK7 Polyclonal Antibody (Product # PA5-84565) in western blot. The relative expression levels of DOK7 within each cell line is shown using RNA-Seq. {RE}

产品信息

PA5-84565

应用

建议稀释比

已发表文章

免疫印迹 (WB)

0.04-0.4 µg/mL

免疫细胞化学 (ICC/IF)

0.25-2 µg/mL

产品规格

种属反应

Human

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

Recombinant protein corresponding to Human DOK7. Recombinant protein control fragment (Product #RP-108476).

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.1 mg/mL

纯化类型

Antigen affinity chromatography

保存液

PBS, pH 7.2, with 40% glycerol

内含物

0.02% sodium azide

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Wet ice

RRID

AB_2791716

产品详细信息

Immunogen sequence: TLQLEKRLSL LSHAGRPGSG GDDRSLSSSS SEASHLDVSA SSRLTAWPEQ SSSSASTSQE

靶标信息

The protein encoded by this gene is essential for neuromuscular synaptogenesis. The protein functions in aneural activation of muscle-specific receptor kinase, which is required for postsynaptic differentiation, and in the subsequent clustering of the acetylcholine receptor in myotubes. This protein can also induce autophosphorylation of muscle-specific receptor kinase. Mutations in this gene are a cause of familial limb-girdle myasthenia autosomal recessive, which is also known as congenital myasthenic syndrome type 1B. Alternative splicing results in multiple transcript variants.

仅用于科研。不用于诊断过程。未经明确授权不得转售。