Invitrogen

DOK7 Monoclonal Antibody (OTI1A9)

DOK7 Antibody in Immunocytochemistry (ICC/IF)

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DOK7 Antibody (MA5-25985) in ICC/IF

Immunofluorescent analysis of DOK7 in COS7 cells. Cells were transfected with a plasmid overexpressing DOK7 and probed with a DOK7 monoclonal antibody (Product # MA5-25985).

DOK7 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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DOK7 Antibody — Antibody specificity was demonstrated by detection of differential basal expression of the target across tissues owing to their inherent genetic constitution. Relative expression of DOK7 was observed in in all mouse tissues except liver and spleen using DOK7 Monoclonal Antibody (OTI1A9) (Product # MA5-25985) in Western Blot. {RE}

产品信息

MA5-25985

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:500-1:2,000

免疫组化（石蜡） (IHC (P))

1:150

免疫细胞化学 (ICC/IF)

1:100

流式细胞分析 (Flow)

1:100

产品规格

种属反应

Human, Mouse

宿主/亚型

Mouse / IgG1

分类

Monoclonal

类型

Antibody

克隆号

OTI1A9

抗原

Full length human recombinant protein of DOK7 produced in HEK293T cell

查看免疫原

偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

1 mg/mL

纯化类型

Affinity Chromatography

保存液

PBS, pH 7.3, with 1% BSA, 50% glycerol

内含物

0.02% sodium azide

保存条件

-20° C, Avoid Freeze/Thaw Cycles

运输条件

Ambient (domestic); Wet ice (international)

AB_2723088

靶标信息

The protein encoded by this gene is essential for neuromuscular synaptogenesis. The protein functions in aneural activation of muscle-specific receptor kinase, which is required for postsynaptic differentiation, and in the subsequent clustering of the acetylcholine receptor in myotubes. This protein can also induce autophosphorylation of muscle-specific receptor kinase. Mutations in this gene are a cause of familial limb-girdle myasthenia autosomal recessive, which is also known as congenital myasthenic syndrome type 1B. Alternative splicing results in multiple transcript variants.

仅用于科研。不用于诊断过程。未经明确授权不得转售。