Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
图: 1 / 3
DP1 Antibody (PA5-110479) in IHC (P)
Immunohistochemistry analysis of DP1 in paraffin-embedded human colon damage. Samples were incubated with DP1 Polyclonal antibody (Product # PA5-110479) using a dilution of 1:200 (40x lens). Perform microwave antigen retrieval with 10 mM PBS buffer pH 7.2 before commencing with IHC staining protocol.
产品信息
PA5-110479
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 1-290 of human DP1/TFDP1 (NP_0090421)
偶联物
形式
Liquid
浓度
2.11 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.01% thimerosal
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2855890
产品详细信息
Immunogen sequence: MAKDAGLIEA NGELKVFIDQ NLSPGKGVVS LVAVHPSTVN PLGKQLLPKT FGQSNVNIAQ QVVIGTPQRP AASNTLVVGS PHTPSTHFAS QNQPSDSSPW SAGKRNRKGE KNGKGLRHFS MKVCEKVQRK GTTSYNEVAD ELVAEFSAAD NHILPNESAY DQKNIRRRVY DALNVLMAMN IISKEKKEIK WIGLPTNSAQ ECQNLEVERQ RRLERIKQKQ SQLQELILQQ IAFKNLVQRN RHAEQQASRP PPPNSVIHLP FIIVNTSKKT VIDCSISNDK FEYLFNFDNT
靶标信息
DP family contains at least two members, DP1 and 2. Structurally, DP1 and 2 are relatively conserved, yet their expression appears to be tissue specific. E2F 1, a functional target for the tumor suppressor protein Rb, heterodimerizes with DP1 and forms an active E2F transcriptional complex. The interaction between members of the E2F and the DP families is mediated, in part, by a leucine repeat which is weakly conserved between the two families.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
篇参考文献 (0)
您是否在文献中引用过该产品？请点击下方按钮邮件告知我们。
生物信息学
蛋白别名: AS1; ASRT1; cell cycle regulatory transcription factor DP1; down-regulated in liver cancer stem cells; DP; DRTF1; DRTF1-polypeptide 1; E2F dimerization partner 1; E2F-related transcription factor; MGC49004; OTTHUMP00000018767; Transcription factor Dp-1
基因别名: DILC; Dp-1; DP1; DRTF1; TFDP1
UniProt ID: (Human) Q14186, (Mouse) Q08639
Entrez Gene ID: (Human) 7027, (Mouse) 21781
transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
cell proliferation
positive regulation of transcription from RNA polymerase II promoter
negative regulation of fat cell proliferation
positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway
mitotic cell cycle
regulation of transcription, DNA-templated
transcription from RNA polymerase II promoter
cell cycle
epidermis development
anoikis
positive regulation of transcription, DNA-templated
regulation of DNA biosynthetic process
