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The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Dolichol-phosphate mannose (Dol-P-Man) serves as a donor of mannosyl residues on the lumenal side of the endoplasmic reticulum (ER). Lack of Dol-P-Man results in defective surface expression of GPI-anchored proteins. Dol-P-Man is synthesized from GDP-mannose and dolichol-phosphate on the cytosolic side of the ER by the enzyme dolichyl-phosphate mannosyltransferase. Human DPM1 lacks a carboxy-terminal transmembrane domain and signal sequence and is regulated by DPM2.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: dolichol monophosphate mannose synthase; dolichol-phosphate (beta-D) mannosyltransferase 1; Dolichol-phosphate mannose synthase subunit 1; Dolichol-phosphate mannosyltransferase subunit 1; Dolichyl-phosphate beta-D-mannosyltransferase subunit 1; dolichyl-phosphate mannosyltransferase 1; dolichyl-phosphate mannosyltransferase polypeptide 1 catalytic subunit; DPM synthase complex, catalytic subunit; DPM synthase subunit 1; Mannose-P-dolichol synthase subunit 1; MPD synthase; MPD synthase subunit 1; OTTMUSP00000017164; RP23-391M18.1
基因别名: AI118379; AI194292; CDGIE; DPM1; MPDS
UniProt ID: (Human) O60762, (Mouse) O70152
Entrez Gene ID: (Human) 8813, (Rat) 296394, (Mouse) 13480