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DPYSL3 Antibody (PA5-119755) in WB
Western blot analysis of CRMP4 on different lysates. Proteins were transferred to a PVDF membrane and blocked with 5% BSA in PBS for 1 hour at room temperature. DPYSL3 Polyclonal Antibody (Product # PA5-119755) at 1:500 was used in 5% BSA at room temperature for 2 hours. Goat Anti-Rabbit IgG - HRP Secondary Antibody at 1:5,000 dilution was used for 1 hour at room temperature. Positive control: Lane 1: Rat spinal cord tissue lysate. Lane 2: LO2 cell lysate.
产品信息
PA5-119755
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide within human CRMP4 1-50
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Affinity chromatography
保存液
TBS, pH 7.4, with 50% glycerol, 0.2% BSA
内含物
0.05% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2913327
产品详细信息
Positive Control: Rat spinal cord tissue lysate, LO2 cell lysate.
Subcellular Location: Cell projection, Cytoplasm.
靶标信息
DPYSL3 is necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. DPYSL3 plays a role in axon guidance, neuronal growth cone collapse and cell migration.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Collapsin response mediator protein 4; collapsin response mediator protein 4 long; CRMP-4; dihydropyrimidinase-like 3; Dihydropyrimidinase-related protein 3; DRP-3; testicular secretory protein Li 7; TOAD-64/Ulip/CRMP; TOAD-64/Ulip/CRMP protein 4b; tuc-4; TUC-4b; ULIP-1; Unc-33-like phosphoprotein 1
基因别名: CRMP-4; CRMP4; DPYSL3; DRP-3; DRP3; LCRMP; TUC-4b; TUC4; ULIP; ULIP-1; ULIP1
UniProt ID: (Human) Q14195, (Mouse) Q62188, (Rat) Q62952
Entrez Gene ID: (Human) 1809, (Mouse) 22240, (Rat) 25418
positive regulation of neuron projection development
negative regulation of neuron projection development
negative regulation of cell migration
neuron development
response to axon injury
actin filament bundle assembly
protein homooligomerization
positive regulation of filopodium assembly
actin crosslink formation
cellular response to cytokine stimulus
nervous system development
pyrimidine nucleobase catabolic process
