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产品信息
PA5-76327
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant full length Human DRD5.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 50% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2720054
产品详细信息
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
靶标信息
The D1 subtype is the most abundant dopamine receptor in the central nervous system. This G-protein coupled receptor stimulates adenylyl cyclase and activates cyclic AMP-dependent protein kinases. D1 receptors regulate neuronal growth and development, mediate some behavioral responses, and modulate dopamine receptor D2-mediated events. Alternate transcription initiation sites result in two transcript variants of this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: D(1B) dopamine receptor; D(5) dopamine receptor; D1b receptor; D1beta dopamine receptor; Dopamine 5 receptor; Dopamine D5 receptor; dopamine receptor D1B; DRD 1B; DRD 5; Hd5dr; MGC10601
基因别名: D5R; DBDR; Drd-5; DRD1B; DRD1L2; DRD5; Gpcr1
UniProt ID: (Human) P21918, (Mouse) Q8BLD9
Entrez Gene ID: (Human) 1816, (Mouse) 13492
synaptic transmission, dopaminergic
response to amphetamine
regulation of systemic arterial blood pressure by vasopressin
norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure
cellular calcium ion homeostasis
adenylate cyclase-activating G-protein coupled receptor signaling pathway
activation of adenylate cyclase activity
adenylate cyclase-activating dopamine receptor signaling pathway
chemical synaptic transmission
learning
associative learning
positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway
transmission of nerve impulse
negative regulation of NAD(P)H oxidase activity
wound healing
response to cocaine
positive regulation of adenylate cyclase activity
negative regulation of blood pressure
regulation of female receptivity
sensitization
phospholipase C-activating dopamine receptor signaling pathway
long term synaptic depression
cellular response to catecholamine stimulus
reactive oxygen species metabolic process
