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产品信息
PA5-56396
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
形式
Liquid
浓度
0.2 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2640808
产品详细信息
Immunogen sequence: KPRCQNVAED MDIQLCASIL NENSDENENI NTMILLDKMH SCSSLEKQQR VNVVQLASPS ENNLVTEKSN LPEYTTEIAG KSKENLLNHE
Highest antigen sequence identity to the following orthologs: Mouse - 33%, Rat - 33%.
靶标信息
As basal cells of stratified squamous epithelia begin to migrate in response to wound healing, they lose their cell-substrate adhesion junctions, the hemidesmosomes. The hemidesmosome is an adhesion structure of the epidermal-dermal junction in keratinocytes. When keratinocytes migrate laterally or upward to differentiate they must control the formation and disintegration of the hemidesmosomes. The bullous pemphigoid antigen BPAG1 is a hemidesmosomal protein of the cutaneous basement membrane zone. The primary sequence deduced from full-length human cDNAs predicts that this molecule consists of a central rod region and flanking globular domains. A neuronal isoform, BPAG1n3 is the result of differential splicing of BPAG1. BPAG1n3 is distinguished by its initial 32 amino acid residues and by the absence of the amino-terminal half of the actin-binding domain.
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生物信息学
蛋白别名: 230 kDa bullous pemphigoid antigen; 230/240 kDa bullous pemphigoid antigen; BPA; Bullous pemphigoid antigen 1; Dystonia musculorum protein; Dystonin; Hemidesmosomal plaque protein; trabeculin-beta
基因别名: BP230; BP240; BPA; BPAG1; CATX-15; CATX15; D6S1101; DMH; DST; DT; EBSB2; HSAN6; KIAA0728; MACF2
UniProt ID: (Human) Q03001
Entrez Gene ID: (Human) 667
