Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
FIGURE: 1 / 2
DUS2/DUS2L Antibody (A305-135A) in WB
Detection of human and mouse DUS2 by western blot. Samples: Whole cell lysate (15 µg) from HeLa, HEK293T, Jurkat, mouse TCMK-1, and mouse NIH 3T3 cells prepared using NETN lysis buffer. Antibody: Affinity purified rabbit anti-DUS2 antibody (Product # A305-135A) (lot A305-135A-1) used for WB at 0.04 µg/mL. Detection: Chemiluminescence with an exposure time of 30 seconds.
Product Details
A305-135A
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Region between residue 443 to 493 of human tRNA-dihydrouridine synthase 2-like.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
phosphate/tris citrate, pH 7-8
Contains
0.09% sodium azide
Storage conditions
4° C
Shipping conditions
Wet ice
Product Specific Information
The recommended shelf life for this product is 1 year from date of receipt.
Target Information
Dihydrouridine synthase catalyzes reduction of the 5,6-double bond of a uridine residue on the displacement loop of tRNA. The resultant modified base, 5,6-dihydrouridine, appears to increase the conformational flexibility and dynamic motion of tRNA (Kato et al., 2005 [PubMed 15994936]).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Have you cited this product in a publication?
Let us know so we can reference it here.
Bioinformatics
Protein Aliases: Dihydrouridine synthase 2; dihydrouridine synthase 2-like, SMM1 homolog; hDUS2; SMM1 homolog; tRNA-dihydrouridine synthase 2-like; tRNA-dihydrouridine(20) synthase (NAD(P)(+)); tRNA-dihydrouridine(20) synthase [NAD(P)+]-like; Up-regulated in lung cancer protein 8; URLC8
Gene Aliases: 2310016K04Rik; DUS2; DUS2L; SMM1; URLC8
UniProt ID: (Human) Q9NX74, (Mouse) Q9D7B1
Entrez Gene ID: (Human) 54920, (Mouse) 66369
double-stranded RNA binding
protein kinase inhibitor activity
protein binding
tRNA dihydrouridine synthase activity
flavin adenine dinucleotide binding
RNA binding
catalytic activity
oxidoreductase activity
enoyl-[acyl-carrier-protein] reductase activity
2,3-dihydroxy-2,3-dihydro-phenylpropionate dehydrogenase activity
cis-2,3-dihydrodiol DDT dehydrogenase activity
trans-9R,10R-dihydrodiolphenanthrene dehydrogenase activity
cis-chlorobenzene dihydrodiol dehydrogenase activity
2,5-dichloro-2,5-cyclohexadiene-1,4-diol dehydrogenase activity
trans-1,2-dihydrodiolphenanthrene dehydrogenase activity
3,4-dihydroxy-3,4-dihydrofluorene dehydrogenase activity
benzo(a)pyrene-trans-11,12-dihydrodiol dehydrogenase activity
benzo(a)pyrene-cis-4,5-dihydrodiol dehydrogenase activity
citronellyl-CoA dehydrogenase activity
menthone dehydrogenase activity
phthalate 3,4-cis-dihydrodiol dehydrogenase activity
cinnamate reductase activity
NADPH-dependent curcumin reductase activity
NADPH-dependent dihydrocurcumin reductase activity
RNA processing factor
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support