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Immunogen sequence: MDSLQKQDLR RPKIHGAVQA SPYQPPTLAS LQRLLWVRQA ATLNHIDEVW PSLFLGDAYA ARDKSKLIQL GITHVVNAAA GKFQVDTGAK FYRGMSLEYY GIEADDNPFF DLSVYFLPVA RYIRAALSVP QGRVLVHCAM GVSRSATLVL AFLMICENMT LVEAIQTVQA HRNICPNSGF LRQLQVLDNR LGRETGRF; Positive Samples: Mouse skeletal muscle, Rat skeletal muscle; Cellular Location: Cytoplasm
DUSP13, a novel DSP, is a member of highly conserved Protein-tyrosine phosphatase super family. Members of this family cooperate with protein kinases and play a vital role in cell cycle regulation. DUSP13 consists of a conserved catalytic domain and is expressed specifically in the testis and skeletal muscle. Based on mRNA localization and expression studies during development, DUSP13 is suggested to be expressed as 3 isoforms due to alternative splicing. Reports suggest DUSP13 might be involved in the regulation of meiosis and differentiation of testicular germ cells during spermatogenesis.
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仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Dsp13-like protein; dual specificity protein phosphatase 13; Dual specificity protein phosphatase 13B; dual specificity protein phosphatase isoform MDSP; Dual specificity tyrosine phosphatase TS-DSP6; dual-specificity tyrosine phosphatase TS-DSP6; DUSP13B; FLJ32450; muscle-restricted DSP; muscle-restricted dual specificity phosphatase; muscle-restricted dual specificity phosphatase; testis and skeletal muscle-specific dual specificity phosphatase; RP11-487I5.6; testis and skeletal muscle-specific dual specificity phosphatase; Testis- and skeletal muscle-specific DSP
基因别名: Dusp13; DUSP13A; DUSP13B; Gm1203; LMW-DSP6; MDSP; TMDP; TS-DSP6
UniProt ID: (Mouse) Q9QYJ7
Entrez Gene ID: (Mouse) 27389, (Rat) 361002