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产品信息
PA5-17984
产品规格
种属反应
Human
宿主/亚型
Goat
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide sequence (AHEMIGTQIVTER) corresponding to the N-terminus amino acids of DUSP16 (aa 2-15).
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Ammonium sulfate precipitation
保存液
TBS, pH 7.3, with 0.5% BSA
内含物
0.02% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_10999957
产品详细信息
This antibody is predicted to react with bovine, canine, mouse and rat based on sequence homology.
This antibody is tested in Peptide ELISA: antibody detection limit dilution 32,000.
Preliminary analysis showed no signal in Western Blot.
靶标信息
Dual-specificity phosphatases constitute a large heterogeneous subgroup of the type I cysteine-based protein-tyrosine phosphatase superfamily. DUSPs are characterized by their ability to dephosphorylate both tyrosine and serine/threonine residues. DUSP16 belongs to a class of DUSPs, designated MKPs, that dephosphorylate MAPK proteins ERK, JNK, and p38 with specificity distinct from that of individual MKP proteins. MKPs contain a highly conserved C-terminal catalytic domain and an N-terminal Cdc25-like domain. MAPK activation cascades mediate various physiologic processes, including cellular proliferation, apoptosis, differentiation, and stress responses.
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生物信息学
蛋白别名: Dual specificity protein phosphatase 16; MAP kinase phosphatase 7; MAPK phosphatase-7; MGC129701; MGC129702; Mitogen-activated protein kinase phosphatase 7
基因别名: DUSP16; KIAA1700; MKP-7; MKP7
UniProt ID: (Human) Q9BY84
Entrez Gene ID: (Human) 80824
