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产品信息
PA1-32629
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic 18 amino acid peptide from near C-terminus of human DUSP26
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS
内含物
0.1% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2095032
产品详细信息
PA1-32629 detects DUSP26 from human samples.
靶标信息
This gene encodes a member of the tyrosine phosphatase family of proteins and exhibits dual specificity by dephosphorylating tyrosine as well as serine and threonine residues. This gene has been described as both a tumor suppressor and an oncogene depending on the cellular context. This protein may regulate neuronal proliferation and has been implicated in the progression of glioblastoma through its ability to dephosphorylate the p53 tumor suppressor. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2015].
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: DSP-4; Dual specificity phosphatase SKRP3; Dual specificity protein phosphatase 26; Low-molecular-mass dual-specificity phosphatase 4; MAP kinase phosphatase 8; MGC1136; MGC2627; Mitogen-activated protein kinase phosphatase 8; neuroendocrine-associated phosphatase; Novel amplified gene in thyroid anaplastic cancer
基因别名: DSP-4; DUSP24; DUSP26; LDP-4; LDP4; MKP-8; MKP8; NATA1; NEAP; SKRP3
UniProt ID: (Human) Q9BV47
Entrez Gene ID: (Human) 78986
negative regulation of transcription from RNA polymerase II promoter
protein dephosphorylation
peptidyl-tyrosine dephosphorylation
negative regulation of protein kinase activity by regulation of protein phosphorylation
positive regulation of cell adhesion
negative regulation of ERK1 and ERK2 cascade
positive regulation of peptidyl-serine dephosphorylation
