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DVL3 Antibody (PA5-115148) in IHC (P)
Immunohistochemistry analysis of DVL3 in human kidney cancer and adjacent normal tissues. Samples were treated with formaldehyde and treated with citrate buffer for antigen retrieval, blocked, and incubated (1.5 hours at 22°C) with polyclonal antibody (Product # PA5-115148) at a dilution of 1:100. Secondary staining was applied with HRP conjugated anti-Rabbit.
产品信息
PA5-115148
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Non-human primate
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human DVL3(Accession Q92997), corresponding to amino acid residues K325-Y375.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Affinity chromatography
保存液
PBS with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice
RRID
AB_2899784
产品详细信息
Antibody detects endogenous levels of total DVL3.
靶标信息
This gene is a member of a multi-gene family which shares strong similarity with the Drosophila disheveled gene, dsh. The Drosophila disheveled gene encodes a cytoplasmic phosphoprotein that regulates cell proliferation.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: dishevelled 3 (homologous to Drosophila dsh); dishevelled, dsh homolog 3; Dishevelled-3; DSH homolog 3; dvl-3; OTTHUMP00000210778; Segment polarity protein dishevelled homolog DVL-3
基因别名: DRS3; DVL3; KIAA0208
UniProt ID: (Human) Q92997, (Mouse) Q61062
Entrez Gene ID: (Human) 1857, (Mouse) 13544
positive regulation of protein phosphorylation
outflow tract septum morphogenesis
Wnt signaling pathway
intracellular signal transduction
non-canonical Wnt signaling pathway
non-canonical Wnt signaling pathway via JNK cascade
response to drug
positive regulation of JUN kinase activity
positive regulation of GTPase activity
positive regulation of transcription, DNA-templated
protein stabilization
canonical Wnt signaling pathway
Wnt signaling pathway, planar cell polarity pathway
negative regulation of canonical Wnt signaling pathway
cochlea morphogenesis
planar cell polarity pathway involved in neural tube closure
regulation of cellular protein localization
beta-catenin destruction complex disassembly
heart morphogenesis
multicellular organism development
