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DVL3 Antibody (PA5-27723) in ICC/IF
Immunocytochemistry-Immunofluorescence analysis of DVL3 was performed in HeLa cells fixed in 4% paraformaldehyde at RT for 15 min. Green: DVL3 Polyclonal Antibody (Product # PA5-27723) diluted at 1:500. Red: phalloidin, a cytoskeleton marker. Blue: Hoechst 33342 staining.
产品信息
PA5-27723
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fragment corresponding to a region within amino acids 1 and 166 of Human Dishevelled 3
偶联物
形式
Liquid
浓度
0.99 mg/mL
纯化类型
Antigen affinity chromatography
保存液
0.1M tris glycine, pH 7, with 10% glycerol
内含物
0.01% thimerosal
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2545199
产品详细信息
Recommended positive controls: HCT116.
Predicted reactivity: Mouse (97%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
靶标信息
This gene is a member of a multi-gene family which shares strong similarity with the Drosophila disheveled gene, dsh. The Drosophila disheveled gene encodes a cytoplasmic phosphoprotein that regulates cell proliferation.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: dishevelled 3 (homologous to Drosophila dsh); dishevelled, dsh homolog 3; Dishevelled-3; DSH homolog 3; dvl-3; OTTHUMP00000210778; Segment polarity protein dishevelled homolog DVL-3
基因别名: DRS3; DVL3; KIAA0208
UniProt ID: (Human) Q92997, (Mouse) Q61062
Entrez Gene ID: (Human) 1857, (Mouse) 13544
positive regulation of protein phosphorylation
outflow tract septum morphogenesis
Wnt signaling pathway
intracellular signal transduction
non-canonical Wnt signaling pathway
non-canonical Wnt signaling pathway via JNK cascade
response to drug
positive regulation of JUN kinase activity
positive regulation of GTPase activity
positive regulation of transcription, DNA-templated
protein stabilization
canonical Wnt signaling pathway
Wnt signaling pathway, planar cell polarity pathway
negative regulation of canonical Wnt signaling pathway
cochlea morphogenesis
planar cell polarity pathway involved in neural tube closure
regulation of cellular protein localization
beta-catenin destruction complex disassembly
heart morphogenesis
multicellular organism development
