Product References
FAM167A is a key molecule to induce BCR-ABL-independent TKI resistance in CML via noncanonical NF-κB signaling activation.
Journal of experimental & clinical cancer research : CR
Yang T,Sim KY,Ko GH,Ahn JS,Kim HJ,Park SG
32-6000 was used in Flow Cytometry to identify the most active transcription factor and its inducer that contribute to BCR-ABL-independent tyrosine kinase inhibitor resistance.
Thu Mar 03 00:00:00 UTC 2022
Elemental and molecular imaging of human full thickness skin after exposure to heavy metals.
Metallomics : integrated biometal science
Chavatte L,Juan M,Mounicou S,Leblanc Noblesse E,Pays K,Nizard C,Bulteau AL
32-6000 was used in Immunohistochemistry (Frozen) to focus on the interaction between four different heavy metals (lead, nickel, cadmium, and mercury) at doses mimicking chronic low-levels of environmental exposure and the effect on skin to get better insight into metal-cell interactions.
Wed Oct 21 00:00:00 UTC 2020
The Differentiation-Associated Keratinocyte Protein Cornifelin Contributes to Cell-Cell Adhesion of Epidermal and Mucosal Keratinocytes.
The Journal of investigative dermatology
Wagner T,Beer L,Gschwandtner M,Eckhart L,Kalinina P,Laggner M,Ellinger A,Gruber R,Kuchler U,Golabi B,Tschachler E,Mildner M
32-6000 was used in Immunohistochemistry to indicate that CNFN is a structural component of the cell adhesion system of differentiated KCs in both epidermis and oral mucosa.
Fri Nov 01 00:00:00 UTC 2019
In vitro Characteristics of Heterogeneous Equine Hoof Progenitor Cell Isolates.
Frontiers in bioengineering and biotechnology
Yang Q,Pinto VMR,Duan W,Paxton EE,Dessauer JH,Ryan W,Lopez MJ
32-6000 was used in Immunocytochemistry to establish and validate in vitro culture of primary progenitor cell isolates from the ectodermal-mesodermal tissue junction in equine hooves, the stratum internum, with and without chronic inflammation known to contribute to lifelong tissue defects.
Wed Sep 30 00:00:00 UTC 2020
The cell-cell junctions of mammalian testes: II. The lamellar smooth muscle monolayer cells of the peritubular wall are laterally connected by vertical adherens junctions-a novel architectonic cell-cell junction system.
Cell and tissue research
Domke LM,Franke WW
32-6000 was used in Immunocytochemistry-immunoflourescence to show the LSMCs of the peritubular wall monolayers are SMCs sensu stricto which are laterally connected by a novel architectonic system of arrays of vertical AJs located in overlapping cell protrusions.
Fri Feb 01 00:00:00 UTC 2019
Fisetin, a 3,7,3',4'-Tetrahydroxyflavone Inhibits the PI3K/Akt/mTOR and MAPK Pathways and Ameliorates Psoriasis Pathology in 2D and 3D Organotypic Human Inflammatory Skin Models.
Cells
Chamcheu JC,Esnault S,Adhami VM,Noll AL,Banang-Mbeumi S,Roy T,Singh SS,Huang S,Kousoulas KG,Mukhtar H
32-6000 was used in Immunohistochemistry to demonstrate the potential of fisetin as an effective and inexpensive agent for the treatment of psoriasis and other related inflammatory skin disorders.
Sun Sep 15 00:00:00 UTC 2019
Role of Fibroblast Growth Factor Receptor 2b in the Cross Talk between Autophagy and Differentiation: Involvement of Jun N-Terminal Protein Kinase Signaling.
Molecular and cellular biology
Nanni M,Ranieri D,Rosato B,Torrisi MR,Belleudi F
32-6000 was used in Western Blotting to point to JNK1 as a signaling hub that regulates the interplay between FGFR2b-induced autophagy and differentiation.
Sun Jul 01 00:00:00 UTC 2018
A non-canonical role for desmoglein-2 in endothelial cells: implications for neoangiogenesis.
Angiogenesis
Ebert LM,Tan LY,Johan MZ,Min KK,Cockshell MP,Parham KA,Betterman KL,Szeto P,Boyle S,Silva L,Peng A,Zhang Y,Ruszkiewicz A,Zannettino AC,Gronthos S,Koblar S,Harvey NL,Lopez AF,Shackleton M,Bonder CS
326000 was used in flow cytometry to study the function of desmoglein-2 and generate knockout mice
Sat Oct 01 00:00:00 UTC 2016
Early dental epithelial transcription factors distinguish ameloblastoma from keratocystic odontogenic tumor.
Journal of dental research
Heikinheimo K,Kurppa KJ,Laiho A,Peltonen S,Berdal A,Bouattour A,Ruhin B,Catón J,Thesleff I,Leivo I,Morgan PR
32-6000 was used in immunohistochemistry to evaluate early dental epithelial transcription factors as a diagnostic marker for ameloblastoma and keratocystic odontogenic tumor
Thu Jan 01 00:00:00 UTC 2015
Desmoglein-1/Erbin interaction suppresses ERK activation to support epidermal differentiation.
The Journal of clinical investigation
Harmon RM,Simpson CL,Johnson JL,Koetsier JL,Dubash AD,Najor NA,Sarig O,Sprecher E,Green KJ
32-6000 was used in Immunohistochemistry-immunoflourescence to identify intermediates responsible for executing the inhibition of ERK by desmoglein-1.
Mon Apr 01 00:00:00 UTC 2013
Alteration of the EphA2/Ephrin-A signaling axis in psoriatic epidermis.
The Journal of investigative dermatology
Gordon K,Kochkodan JJ,Blatt H,Lin SY,Kaplan N,Johnston A,Swindell WR,Hoover P,Schlosser BJ,Elder JT,Gudjonsson JE,Getsios S
32-6000 was used in western blot to assess if the EphA2/ephrin-A1 signaling axis is altered in psoriasis.
Fri Mar 01 00:00:00 UTC 2013
Gastro-oesophageal reflux disease is associated with up-regulation of desmosomal components in oesophageal mucosa.
Histopathology
Wex T,Mönkemüller K,Stahr A,Kuester D,Fry LC,Völkel S,Kandulski A,Roessner A,Malfertheiner P
32-6000 was used in immunohistochemistry to examine the role of desmosomal proteins in gastro-oesophageal reflux disease.
Wed Feb 01 00:00:00 UTC 2012
Hailey-Hailey disease and tight junctions: Claudins 1 and 4 are regulated by ATP2C1 gene encoding Ca(2+) /Mn(2+) ATPase SPCA1 in cultured keratinocytes.
Experimental dermatology
Raiko L,Siljamäki E,Mahoney MG,Putaala H,Suominen E,Peltonen J,Peltonen S
Wed Aug 01 00:00:00 UTC 2012
EGFR regulation of epidermal barrier function.
Physiological genomics
Tran QT,Kennedy LH,Leon Carrion S,Bodreddigari S,Goodwin SB,Sutter CH,Sutter TR
Sun Apr 15 00:00:00 UTC 2012
EGFR regulation of epidermal barrier function.
Physiological genomics
Tran QT,Kennedy LH,Leon Carrion S,Bodreddigari S,Goodwin SB,Sutter CH,Sutter TR
Sun Apr 15 00:00:00 UTC 2012
Assessment of desmosomal components (desmoglein 1-3, plakoglobin) in cardia mucosa in relation to gastroesophageal reflux disease and Helicobacter pylori infection.
Human pathology
Wex T,Kuester D,Mönkemüller K,Stahr A,Fry LC,Kandulski A,Kropf S,Roessner A,Malfertheiner P
32-6000 was used in immunohistochemistry to examine the contribution of the desmosomal compartment to gastroesophageal reflux disease.
Mon Oct 01 00:00:00 UTC 2012
Human eccrine sweat gland cells can reconstitute a stratified epidermis.
The Journal of investigative dermatology
Biedermann T,Pontiggia L,Böttcher-Haberzeth S,Tharakan S,Braziulis E,Schiestl C,Meuli M,Reichmann E
Sun Aug 01 00:00:00 UTC 2010
Ligand targeting of EphA2 enhances keratinocyte adhesion and differentiation via desmoglein 1.
Molecular biology of the cell
Lin S,Gordon K,Kaplan N,Getsios S
32-6000 was used in western blot to suggest that EphA2-expressing keratinocytes respond to ephrin-A1-based cues from their neighbors to facilitate entry into a terminal differentiation pathway
Mon Nov 15 00:00:00 UTC 2010
Ligand targeting of EphA2 enhances keratinocyte adhesion and differentiation via desmoglein 1.
Molecular biology of the cell
Lin S,Gordon K,Kaplan N,Getsios S
32-6000 was used in western blot to suggest that EphA2-expressing keratinocytes respond to ephrin-A1-based cues from their neighbors to facilitate entry into a terminal differentiation pathway
Mon Nov 15 00:00:00 UTC 2010
P120 catenin is associated with desmogleins when desmosomes are assembled in high-Ca2+ medium but not when disassembled in low-Ca2+ medium in DJM-1 cells.
The Journal of dermatology
Kanno M,Aoyama Y,Isa Y,Yamamoto Y,Kitajima Y
32-6000 was used in immunoprecipitation to test if p120ctn associates with Dsg1 and Dsg3 in keratinocytes
Sun Jun 01 00:00:00 UTC 2008
New skin-equivalent model from de-epithelialized amnion membrane.
Cell and tissue research
Yang L,Shirakata Y,Shudou M,Dai X,Tokumaru S,Hirakawa S,Sayama K,Hamuro J,Hashimoto K
32-6000 was used in immunohistochemistry - paraffin section to develop a living skin-equivalent from de-epithelialized amnion membrane
Sun Oct 01 00:00:00 UTC 2006