Invitrogen

Desmoplakin Polyclonal Antibody

Desmoplakin Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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Desmoplakin Antibody (PA5-142588) in IHC (P)

Immunohistochemistry analysis of Desmoplakin in human heart. Samples were incubated with Desmoplakin polyclonal antibody (Product # PA5-142588) using a dilution of 3.75 µg/mL. Formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

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产品信息

PA5-142588

应用

建议稀释比

已发表文章

免疫组化（石蜡） (IHC (P))

3-6 µg/mL

产品规格

种属反应

Human

宿主/亚型

Goat / IgG

分类

Polyclonal

类型

Antibody

抗原

Peptide with sequence C-QESVKQAHLRNEH.

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.5 mg/mL

纯化类型

Ammonium sulfate precipitation

保存液

TBS, pH 7.3, with 0.5% BSA

内含物

0.02% sodium azide

保存条件

-20° C, Avoid Freeze/Thaw Cycles

运输条件

Wet ice

AB_2933234

产品详细信息

Additional Information: This antibody is expected to recognize reported isoform I (NP_004406.2) only.

This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:4,000.

Preliminary analysis showed no signal in Western Blot.

靶标信息

Desmoplakin (DSP) is a major high molecular weight protein of the desmosomes. It is involved in the organization of the desmosomal cadherin-plakoglobin complexes into discrete plasma membrane domains and in the anchoring of intermediate filaments to the desmosomes. Desmoplakin mutations are associated with Keratoderma and cardiomyopathy.

仅用于科研。不用于诊断过程。未经明确授权不得转售。