Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
图: 1 / 3
Dnmt2 Antibody (MA5-16197) in ICC/IF
Immunofluorescence analysis of Dnmt2 Monoclonal Antibody was performed using 70% confluent log phase MCF-7 cells. The cells were fixed with 4% paraformaldehyde for 10 minutes, permeabilized with 0.1% Triton™ X-100 for 10 minutes, and blocked with 1% BSA for 1 hour at room temperature. The cells were labeled with Dnmt2 (102B1259.2) Mouse Monoclonal Antibody (Product # MA5-16197) at 2 µg/mL in 0.1% BSA, incubated for 3 hours at room temperature and then labeled with Goat anti-Mouse IgG (H+L) Superclonal™ Secondary Antibody, Alexa Fluor® 488 ... View More
产品信息
MA5-16197
产品规格
种属反应
Human,
Mouse,
Zebrafish
宿主/亚型
Mouse
/ IgG1, kappa
分类
Monoclonal
类型
Antibody
克隆号
102B1259.2
抗原
Synthetic peptides corresponding to mouse Dnmt2.
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Protein G
保存液
PBS with 0.2% gelatin
内含物
0.05% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2537716
靶标信息
CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a protein with similarity to DNA methyltransferases, but this protein does not display methyltransferase activity. The protein strongly binds DNA, suggesting that it may mark specific sequences in the genome. Alternative splicing results in multiple transcript variants encoding different isoforms.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
篇参考文献 (0)
您是否在文献中引用过该产品？请点击下方按钮邮件告知我们。
生物信息学
蛋白别名: DNA (cytosine-5)-methyltransferase-like protein 2; DNA (cytosine-5-)-methyltransferase 2; DNA cytosine-5 methyltransferase 2; DNA methyltransferase; DNA methyltransferase 2; DNA methyltransferase homolog HsaIIP; DNA methyltransferase homolog MmuIIP; DNA methyltransferase-2; DNA MTase homolog HsaIIP; DNA MTase homolog MmuIIP; Dnmt2; M.HsaIIP; m.MmuIIP; Met-2; PuMet; RP11-406H21.1; tRNA (cytosine(38)-C(5))-methyltransferase; tRNA (cytosine-5-)-methyltransferase
基因别名: DMNT2; DNMT2; im:7138158; Met2; MHSAIIP; PUMET; RNMT1; Rnmt2; TRDMT1; zgc:136961
UniProt ID: (Human) O14717, (Mouse) O55055
Entrez Gene ID: (Human) 1787, (Mouse) 13434, (Zebrafish) 449878
