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产品信息
D5R-FITC
产品规格
种属反应
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide taken within amino acid region 428-478 on mouseDopamine Receptor D5 protein.
偶联物
激发/发射光谱
498/517 nm
查看光谱
形式
Liquid
浓度
0.5-1.5 mg/mL
纯化类型
Affinity chromatography
保存液
proprietary buffer, pH 7.4-7.8, with 30% glycerol, 0.5% BSA
内含物
0.02% sodium azide
保存条件
-20° C, store in dark
运输条件
Ambient (domestic); Wet ice (international)
靶标信息
The D1 subtype is the most abundant dopamine receptor in the central nervous system. This G-protein coupled receptor stimulates adenylyl cyclase and activates cyclic AMP-dependent protein kinases. D1 receptors regulate neuronal growth and development, mediate some behavioral responses, and modulate dopamine receptor D2-mediated events. Alternate transcription initiation sites result in two transcript variants of this gene.
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生物信息学
蛋白别名: D(1B) dopamine receptor; D(5) dopamine receptor; D1b receptor; Dopamine 5 receptor; Dopamine D5 receptor; dopamine receptor 5; DRD 1B; DRD 5; Hd5dr; MGC10601
基因别名: D1B; D5R; Drd-5; Drd1b; Drd5; Gpcr1
UniProt ID: (Mouse) Q8BLD9, (Rat) P25115
Entrez Gene ID: (Mouse) 13492, (Rat) 25195
synaptic transmission, dopaminergic
response to amphetamine
regulation of systemic arterial blood pressure by vasopressin
norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure
negative regulation of protein kinase activity
adenylate cyclase-activating G-protein coupled receptor signaling pathway
adenylate cyclase-activating dopamine receptor signaling pathway
dopamine receptor signaling pathway
chemical synaptic transmission
mating behavior
associative learning
visual learning
positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway
transmission of nerve impulse
negative regulation of cell migration
positive regulation of cAMP biosynthetic process
negative regulation of NAD(P)H oxidase activity
wound healing
response to cocaine
positive regulation of adenylate cyclase activity
negative regulation of blood pressure
regulation of female receptivity
sensitization
regulation of long-term neuronal synaptic plasticity
long term synaptic depression
cellular response to catecholamine stimulus
reactive oxygen species metabolic process
