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This antibody is specific for the ~75 kDa DBH protein in Western blots of human adrenal medulla. It also recognizes DBH in monkey and mouse tissues.
The protein encoded by this gene is an oxidoreductase belonging to the copper type II, ascorbate-dependent monooxygenase family. It is present in the synaptic vesicles of postganglionic sympathetic neurons and converts dopamine to norepinephrine. It exists in both soluble and membrane-bound forms, depending on the absence or presence, respectively, of a signal peptide.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Dopamine beta-hydroxylase; dopamine beta-hydroxylase (dopamine beta-monooxygenase); Dopamine beta-monooxygenase; Dopamine-Beta-hydroxylase; Soluble dopamine beta-hydroxylase
Gene Aliases: DBH; DBM
UniProt ID: (Human) P09172, (Mouse) Q64237
Entrez Gene ID: (Human) 1621, (Mouse) 13166
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