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产品信息
1627-MSM1-P1
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG1, kappa
分类
Monoclonal
类型
Antibody
克隆号
DBN1, 2879
抗原
Recombinant fragment (aa 150-281) of human DBN1 protein
偶联物
形式
Liquid
浓度
200 µg/mL
纯化类型
Protein G
保存液
PBS, pH 7.4, with 0.05% BSA
内含物
0.05% sodium azide
保存条件
4° C
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Immunohistochemistry (PFA fixed): incubate antibody for 30 min RT. Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95 degrees C followed by cooling at RT for 20 minutes.
靶标信息
The protein encoded by this gene is a cytoplasmic actin-binding protein thought to play a role in the process of neuronal growth. It is a member of the drebrin family of proteins that are developmentally regulated in the brain. A decrease in the amount of this protein in the brain has been implicated as a possible contributing factor in the pathogenesis of memory disturbance in Alzheimer's disease. At least two alternative splice variants encoding different protein isoforms have been described for this gene.
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生物信息学
蛋白别名: Developmentally-regulated brain protein; DKFZp434D064; Drebrin; drebrin E; drebrin E2; drebrin-1
基因别名: D0S117E; DBN1
UniProt ID: (Human) Q16643
Entrez Gene ID: (Human) 1627
