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Recommended positive controls: SK-N-SH, IMR-32, SK-N-AS, NT2D1, IMR32, mouse brain, rat brain.
Predicted reactivity: Mouse (82%), Rat (81%), Bovine (85%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
The protein encoded by this gene is a cytoplasmic actin-binding protein thought to play a role in the process of neuronal growth. It is a member of the drebrin family of proteins that are developmentally regulated in the brain. A decrease in the amount of this protein in the brain has been implicated as a possible contributing factor in the pathogenesis of memory disturbance in Alzheimer's disease. At least two alternative splice variants encoding different protein isoforms have been described for this gene.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Developmentally-regulated brain protein; DKFZp434D064; Drebrin; drebrin A; drebrin E; drebrin E2; drebrin-1
基因别名: D0S117E; DBN1; Drba
UniProt ID: (Human) Q16643, (Rat) Q07266, (Mouse) Q9QXS6
Entrez Gene ID: (Human) 1627, (Rat) 81653, (Mouse) 56320