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产品信息
PA5-83472
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
形式
Liquid
浓度
0.05 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2790627
产品详细信息
Immunogen sequence: GLGVKETPQQ KYQRLLHEVQ ELTTEVEKIK TTVKESATEE KLTPVLLAKQ LAALKQQLVA SHLEKLLGPD AAINLTDPDG ALAKRLLLQL EATKNSKG
靶标信息
This gene encodes a 50-kD subunit of dynactin, a macromolecular complex consisting of 10-11 subunits ranging in size from 22 to 150 kDa. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit is present in 4-5 copies per dynactin molecule. It contains three short alpha-helical coiled-coil domains that may mediate association with self or other dynactin subunits. It may interact directly with the largest subunit (p150) of dynactin and may affix p150 in place.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 50 kDa dynein-associated polypeptide; DCTN-50; dynactin 2 (p50); Dynactin complex 50 kDa subunit; Dynactin subunit 2; epididymis secretory protein Li 77; GMP23-48K; Growth cone membrane protein 23-48K; p50 dynamitin
基因别名: 2310042E05Rik; C130077D06Rik; C87049; DCTN-50; DCTN2; DCTN50; DYNAMITIN; GMP23-48K; HEL-S-77; p50; RBP50
UniProt ID: (Human) Q13561, (Rat) Q6AYH5, (Mouse) Q99KJ8
Entrez Gene ID: (Human) 10540, (Rat) 299850, (Mouse) 69654
G2/M transition of mitotic cell cycle
ER to Golgi vesicle-mediated transport
microtubule-based process
mitotic spindle organization
mitotic nuclear division
cell proliferation
antigen processing and presentation of exogenous peptide antigen via MHC class II
melanosome transport
protein localization to centrosome
metabolic process
