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产品信息
PA5-90253
产品规格
种属反应
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 410-555 of human Dynamin 3 (NP_0012651811)
偶联物
形式
Liquid
浓度
2.34 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.01% thimerosal
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2805984
产品详细信息
Immunogen sequence: EAIVKKQIVK LKGPSLKSVD LVIQELINTV KKCTKKLANF PRLCEETERI VANHIREREG KTKDQVLLLI DIQVSYINTN HEDFIGFANA QQRSSQVHKK TTVGNQVIRK GWLTISNIGI MKGGSKGYWF VLTAESLSWY KDDENI; Positive Samples: mouse brain, rat brain; Cellular Location: Cytoplasm, cytoskeleton
靶标信息
The dynamins are a family of 100 kDa GTPases transcribed from at least three separate genes. At least four mRNA splice variants for each dynamin have been described. Dynamins contain several conserved regions including the conserved, amino-terminal GTPase domain, a centrally located membrane-binding plekstrin homology domain (PHD), and a coiled-coil region located in front of a proline-rich domain (PRD). The PRD is thought to mediate interactions between dynamin and numerous other cellular proteins. Dynamin I is expressed exclusively in neurons, dynamin II is ubiquitously expressed, and dynamin III is thought to be restricted to expression in the brain, testis, heart, and lung. The dynamins participate in the cellular process of clathrin-mediated and fluid-phase endocytosis.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Dyna III; Dynamin III; Dynamin, testicular; Dynamin-3; T-dynamin; testicular dynamin
基因别名: 9630020E24Rik; AW061159; B230343F03Rik; C530045C17; Dnm3; Dyn3; dynamin-2; Kiaa0820; mKIAA0820
UniProt ID: (Mouse) Q8BZ98, (Rat) Q08877
Entrez Gene ID: (Mouse) 103967, (Rat) 171574
