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E2F7 Antibody (PA5-114731) in IHC (P)
Immunohistochemistry analysis of E2F7 in human spleen tissue. Samples were treated with formaldehyde and treated with citrate buffer for antigen retrieval, blocked, and incubated (1.5 hours at 22°C) with polyclonal antibody (Product # PA5-114731) at a dilution of 1:100. Secondary staining was applied with HRP conjugated goat anti-rabbit.
产品信息
PA5-114731
产品规格
种属反应
Human,
Mouse,
Non-human primate,
Rat
已发表种属
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human E2F7(Accession Q96AV8), corresponding to amino acid residues N33-P83.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Affinity chromatography
保存液
PBS with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice
RRID
AB_2899367
产品详细信息
Antibody detects endogenous levels of total E2F7.
靶标信息
E2F transcription factors, such as E2F7, play an essential role in the regulation of cell cycle progression.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: E2F-7; FLJ12981; no; Transcription factor E2F7
基因别名: A630014C11Rik; D10Ertd739e; E2F-7; E2F7
UniProt ID: (Human) Q96AV8, (Mouse) Q6S7F2, (Rat) D4A4D7
Entrez Gene ID: (Human) 144455, (Mouse) 52679, (Rat) 314818
RNA polymerase II regulatory region sequence-specific DNA binding
core promoter binding
transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding
transcription factor activity, sequence-specific DNA binding
transcription corepressor activity
protein binding
identical protein binding
DNA binding
RNA metabolism protein
nucleic acid metabolism protein
general transcription factor
negative regulation of transcription from RNA polymerase II promoter
placenta development
sprouting angiogenesis
transcription, DNA-templated
DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
negative regulation of cell proliferation
DNA damage response, signal transduction by p53 class mediator
negative regulation of cytokinesis
positive regulation of DNA endoreduplication
positive regulation of transcription from RNA polymerase II promoter
trophoblast giant cell differentiation
chorionic trophoblast cell differentiation
hepatocyte differentiation
negative regulation of transcription involved in G1/S transition of mitotic cell cycle
negative regulation of G1/S transition of mitotic cell cycle
regulation of transcription, DNA-templated
transcription from RNA polymerase II promoter
cellular response to DNA damage stimulus
cell cycle
