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EDG4 Antibody (PA5-102074) in IHC (P)
Immunohistochemistry analysis of EDG4 in mouse testis tissue. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. Samples were incubated with EDG4 polyclonal antibody (Product # PA5-102074) using a dilution of 1:100 (4°C overnight) followed by HRP conjugated anti-Rabbit secondary antibody.
产品信息
PA5-102074
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Non-human primate
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human LPAR2(Accession Q9HBW0), corresponding to amino acid residues Y295-P345.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice
RRID
AB_2851501
产品详细信息
Antibody detects endogenous levels of total EDG4.
靶标信息
Edg4 is a Lysophospholipid/Lysosphingolipid Receptor activated by phosphatidic acid (PA) and lysophosphatidic acid (LPA). It enhances the transcription of serum response element (SRE) reporter genes. In CD4(+) T cells, Edg4 may be involved in the control of interleukin-2 secretion. Edg4 expression has been documented in leukocytes, pancreas, spleen, thymus, prostate, and testis. Edg4 expression has also been seen in many cancer cell lines, including those of brain, blood, breast, ovary, cervix, colon, skin, and thyroid. ESTs have been isolated from B-cell/lung/testis, blood, brain, embryo, heart/melanocyte/uterus, liver, placenta, prostate, and skin libraries.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: endothelial differentiation, lysophosphatidic acid G-protein-coupled receptor 4; endothelial differentiation, lysophosphatidic acid G-protein-coupled receptor, 4; G protein-coupled receptor; LPA receptor 2; LPA receptor EDG4; LPA-2; LPA2 Receptor; Lysophosphatidic acid receptor 2; Lysophosphatidic acid receptor Edg-4; lysophosphatidic acid receptor EDG4
基因别名: EDG-4; EDG4; IPA2; LPA-2; LPA2; Lpar2
UniProt ID: (Mouse) Q9JL06
Entrez Gene ID: (Human) 9170, (Mouse) 53978
