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产品信息
OSE00037W-100UL
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
已发表种属
Not Applicable
宿主/亚型
Rabbit
/ Ig
分类
Polyclonal
类型
Antibody
抗原
A synthetic peptide from c-terminal region of human Endothelin-1 receptor (EDNRA) conjugated to an immunogenic carrier protein was used as the antigen
偶联物
形式
Lyophilized
浓度
Conc. Not Determined
保存液
whole serum
内含物
no preservative
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability.
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Reconstitute in 100 µL of MQ water. Centrifuge to remove any insoluble material.
Specificity of this antibody: EDNRA.
靶标信息
This gene encodes the receptor for endothelin-1, a peptide that plays a role in potent and long-lasting vasoconstriction. This receptor associates with guanine-nucleotide-binding (G) proteins, and this coupling activates a phosphatidylinositol-calcium second messenger system. Polymorphisms in this gene have been linked to migraine headache resistance. Alternative splicing results in multiple transcript variants.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: Endothelin A; endothelin receptor subtype A; Endothelin receptor type A; Endothelin-1 receptor; endothelin-1-specific receptor; ET-A; G protein-coupled receptor
基因别名: EDNRA; ET-A; ETA; ETA-R; ETAR; ETRA; hET-AR; MFDA
UniProt ID: (Human) P25101
Entrez Gene ID: (Human) 1909
patterning of blood vessels
response to hypoxia
in utero embryonic development
histamine secretion
glomerular filtration
smooth muscle contraction
signal transduction
G-protein coupled receptor signaling pathway
activation of adenylate cyclase activity
activation of phospholipase C activity
positive regulation of cytosolic calcium ion concentration
protein kinase C-activating G-protein coupled receptor signaling pathway
Rho protein signal transduction
heart development
aging
respiratory gaseous exchange
regulation of blood pressure
cell proliferation
positive regulation of cell proliferation
neural crest cell development
artery smooth muscle contraction
glucose transport
sensory perception of pain
negative regulation of cAMP biosynthetic process
response to lipopolysaccharide
vasoconstriction
positive regulation of odontogenesis
negative regulation of apoptotic process
penile erection
response to morphine
fibroblast proliferation
enteric nervous system development
smooth muscle cell proliferation
regulation of epithelial cell proliferation
positive regulation of inflammatory response
positive regulation of release of sequestered calcium ion into cytosol
positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway
maternal process involved in parturition
head development
positive regulation of ERK1 and ERK2 cascade
cellular response to mechanical stimulus
endothelin receptor signaling pathway
positive regulation of neutrophil chemotaxis
positive regulation of kidney development
