Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
产品信息
A301-642A
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Region between residue 25 and 75 of human euchromatic histone-lysine N-methyltransferase 1.
偶联物
形式
Liquid
浓度
0.20 mg/mL
纯化类型
Antigen affinity chromatography
保存液
TBS, pH 7.0 to 8.0, with 0.1% BSA
内含物
0.09% sodium azide
保存条件
4° C
运输条件
Wet ice
产品详细信息
The recommended shelf life for this product is 1 year from date of receipt.
Application Note: For IHC, epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
靶标信息
EHMT1, also known as EUHMTASE1, is a histone methyltransferase. This protein methylates 'Lys-9' of histone H3 in vitro. H3 'Lys-9' methylation represents a specific tag for epigenetic transcriptional repression by recruiting HP1 proteins to methylated histones. EHMT1 is Probably targeted to histone H3 by different DNA-binding proteins like E2F6, MGA, MAX and/or DP1. During G0 phase, it probably contributes to silencing of MYC- and E2F-responsive genes, suggesting a role in the G0/G1 transition of the cell cycle.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
篇参考文献 (0)
您是否在文献中引用过该产品？请点击下方按钮邮件告知我们。
生物信息学
蛋白别名: Eu-HMTase1; Euchromatic histone-lysine N-methyltransferase 1; G9a-like protein 1; GLP; H3-K9-HMTase 5; Histone H3-K9 methyltransferase 5; Histone-lysine N-methyltransferase EHMT1; histone-lysine N-methyltransferase, H3 lysine-9 specific 5; Lysine N-methyltransferase 1D
基因别名: bA188C12.1; EHMT1; Eu-HMTase1; EUHMTASE1; FP13812; GLP; GLP1; KIAA1876; KMT1D
UniProt ID: (Human) Q9H9B1
Entrez Gene ID: (Human) 79813
negative regulation of transcription from RNA polymerase II promoter
DNA methylation
embryo development
chromatin modification
histone methylation
peptidyl-lysine monomethylation
peptidyl-lysine dimethylation
negative regulation of transcription, DNA-templated
histone H3-K9 methylation
response to fungicide
histone H3-K27 methylation
regulation of signal transduction by p53 class mediator
