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产品信息
PA5-116806
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 30-100 of human EIF2B4 (Q9UI10)
偶联物
形式
Liquid
浓度
0.88 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.01% thimerosal
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2901437
产品详细信息
Positive Samples: Mouse brain, Rat testis, Rat brain
Immunogen sequence: EMTKEEKLQL RKEKKQQKKK RKEEKGAEPE TGSAVSAAQC QVGPTRELPE SGIQLGTPRE KVPAGRSKAE L
靶标信息
Eukaryotic initiation factor 2B (EIF2B), which is necessary for protein synthesis, is a GTP exchange factor composed of five different subunits. The protein encoded by this gene is the fourth, or delta, subunit. Defects in this gene are a cause of leukoencephalopathy with vanishing white matter (VWM) and ovarioleukodystrophy. Multiple transcript variants encoding different isoforms have been found for this gene.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: DKFZp586J0119; eIF-2B GDP-GTP exchange factor subunit delta; eIF2B GDP-GTP exchange factor subunit delta; eukaryotic translation initiation factor 2B subunit 4 delta; eukaryotic translation initiation factor 2B, subunit 4 delta, 67kDa; translation initiation factor eIF-2b delta subunit; translation initiation factor eIF-2B subunit delta; Translation initiation factor eIF2B subunit delta
基因别名: EIF-2B; EIF2B; EIF2B4; EIF2BD; EIF2Bdelta; Jgr1a
UniProt ID: (Human) Q9UI10, (Rat) Q63186, (Mouse) Q61749
Entrez Gene ID: (Human) 8890, (Rat) 117019, (Mouse) 13667
ovarian follicle development
translational initiation
regulation of translation
response to heat
response to glucose
oligodendrocyte development
L-methionine biosynthetic process from methylthioadenosine
negative regulation of translational initiation in response to stress
myelination
response to peptide hormone
positive regulation of GTPase activity
negative regulation of translational initiation
cellular response to stimulus
cellular metabolic process
translation
