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产品信息
PA5-144963
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence. Antigen range: 27-104.
偶联物
形式
Liquid
浓度
0.8 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_3091725
产品详细信息
Immunogen sequence: VGREMTKEEK LQLRKEKKQQ KKKRKEEKGA EPETGSAVSA AQCQVGPTRE LPESGIQLGT PREKVPAGRS KAELRAER
Antigen sequence identity: Mouse 78%; Rat 77%
靶标信息
Eukaryotic initiation factor 2B (EIF2B), which is necessary for protein synthesis, is a GTP exchange factor composed of five different subunits. The protein encoded by this gene is the fourth, or delta, subunit. Defects in this gene are a cause of leukoencephalopathy with vanishing white matter (VWM) and ovarioleukodystrophy. Multiple transcript variants encoding different isoforms have been found for this gene.
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生物信息学
蛋白别名: DKFZp586J0119; eIF-2B GDP-GTP exchange factor subunit delta; eIF2B GDP-GTP exchange factor subunit delta; eukaryotic translation initiation factor 2B subunit 4 delta; eukaryotic translation initiation factor 2B, subunit 4 delta, 67kDa; translation initiation factor eIF-2b delta subunit; Translation initiation factor eIF2B subunit delta
基因别名: EIF-2B; EIF2B; EIF2B4; EIF2BD; EIF2Bdelta
UniProt ID: (Human) Q9UI10
Entrez Gene ID: (Human) 8890
ovarian follicle development
translational initiation
regulation of translation
response to heat
response to glucose
oligodendrocyte development
L-methionine biosynthetic process from methylthioadenosine
negative regulation of translational initiation in response to stress
myelination
response to peptide hormone
positive regulation of GTPase activity
negative regulation of translational initiation
cellular response to stimulus
