Invitrogen

EIF4A1/EIF4A2/EIF4A3 Polyclonal Antibody

EIF4A1/EIF4A2/EIF4A3 Antibody in Immunocytochemistry (ICC/IF)

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EIF4A1/EIF4A2/EIF4A3 Antibody (PA5-116950) in ICC/IF

Immunofluorescence analysis of EIF4A1/EIF4A2/EIF4A3 in NIH-3T3 cells. Samples were incubated with EIF4A1/EIF4A2/EIF4A3 Polyclonal antibody (Product # PA5-116950) using a dilution of 1:100 (40x lens). Blue: DAPI for nuclear staining.

EIF4A1/EIF4A2/EIF4A3 Antibody in Western Blot (WB)

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产品信息

PA5-116950

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:500-1:1,000

免疫细胞化学 (ICC/IF)

1:50-1:200

酶联免疫吸附实验 (ELISA)

1 µg/mL

产品规格

种属反应

Human, Mouse, Rat

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

A synthetic peptide corresponding to a sequence within amino acids 1-100 of human eIF4A (NP_0014071)

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

1.638 mg/mL

纯化类型

Affinity chromatography

保存液

PBS, pH 7.3, with 50% glycerol

内含物

0.05% ProClin 300

保存条件

-20° C, Avoid Freeze/Thaw Cycles

运输条件

Wet ice

AB_2901580

产品详细信息

Positive Samples: 293T, HeLa, HepG2, MCF7, C2C12, Mouse brain, Rat brain

Immunogen sequence: MSASQDSRSR DNGPDGMEPE GVIESNWNEI VDSFDDMNLS ESLLRGIYAY GFEKPSAIQQ RAILPCIKGY DVIAQAQSGT GKTATFAISI LQQIELDLKA

靶标信息

The eIF4A proteins are involved in many aspects of RNA metabolism due to their RNA-binding capacity and ATPase activity. eIF4A1 and eIF4A2 are cytoplasmic, whereas eIF4A3 is nuclear-localized. In the current model of translation initiation, eIF4A unwinds RNA secondary structures in the 5'-UTR of mRNAs which is necessary to allow efficient binding of the small ribosomal subunit, and subsequent scanning for the initiator codon.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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生物信息学

蛋白别名: ATP-dependent RNA helicase DDX48; ATP-dependent RNA helicase eIF4A-1; ATP-dependent RNA helicase eIF4A-2; ATP-dependent RNA helicase eIF4A-3; DEAD (Asp-Glu-Ala-Asp) box polypeptide 48; DEAD box protein 48; eIF-4A-I; eIF-4A-II; eIF-4A-III; eIF4A-I; eIF4A-II; eIF4A-III; Eukaryotic initiation factor 4A-I; Eukaryotic initiation factor 4A-II; Eukaryotic initiation factor 4A-III; Eukaryotic initiation factor 4A-like NUK-34; eukaryotic initiation factor 4AI; Eukaryotic translation initiation factor 4A isoform 3; eukaryotic translation initiation factor 4A, isoform 1; eukaryotic translation initiation factor 4A, isoform 2; eukaryotic translation initiation factor 4A, isoform 3; hNMP 265; initiation factor eIF-4A long form; NMP 265; Nuclear matrix protein 265; protein synthesis initiation factor 4AII

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基因别名: 2400003O03Rik; 4833432N07Rik; BM-010; DDX2A; DDX2B; DDX48; EIF-4A; eIF-4A-I; eIF-4A-II; Eif4; EIF4A; eIF4A-I; eIF4A-II; eIF4A-III; EIF4A1; EIF4A2; EIF4A3; eIF4AIII; EIF4F; KIAA0111; mKIAA0111; MUK34; NMP265; NUK34; RCPS